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Infection and Immunity, November 2009, p. 4690-4695, Vol. 77, No. 11
0019-9567/09/$08.00+0     doi:10.1128/IAI.01515-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

MINIREVIEW

Susceptibility to Infectious Diseases Based on Antimicrobial Peptide Production{triangledown}

Bruno Rivas-Santiago, Carmen J. Serrano, and J. Antonio Enciso-Moreno*

Unidad de Investigación Médica Zacatecas, Instituto Mexicano del Seguro Social (IMSS), Zacatecas City, Mexico

In the last few years, the great impact of antimicrobial peptides on infectious disease susceptibility and natural resistance has been reported. In some cases, susceptibility to diseases is related to antimicrobial peptide polymorphisms and gene copy numbers, but for the vast majority of infectious diseases, these phenomena need to be elucidated. This review is focused on the current knowledge about susceptibility and resistance conferred by genetic variations in antimicrobial peptide expression in infectious diseases.

* Corresponding author. Mailing address: Unidad de Investigación Médica-Zacatecas, IMSS, Interior de la Alameda #45, Zacatecas, Zacatecas, México. Phone and fax: 524929221881. E-mail: rondo_vm{at}yahoo.com

{triangledown} Published ahead of print on 24 August 2009.

Editor: J. B. Kaper

Infection and Immunity, November 2009, p. 4690-4695, Vol. 77, No. 11
0019-9567/09/$08.00+0     doi:10.1128/IAI.01515-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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